Synthetic Peptides

Synthetic peptides are a class of molecules particularly suitable for the therapeutic inhibition of protein/protein interactions. 

ANBITION is currently in the discovery/early preclinical phase with different peptides.

They can be easily produced by chemical synthesis, can have very high affinity for the target molecules for their ability to adapt on the surface of biomolecules, can be engineered to adopt defined three-dimensional structures that require less conformational transitions to adapt to the binding sites, can be engineered to increase their stability in biological media and in vivo, are particularly suitable for extracellular biological targets such as receptors and soluble ligands involved in angiogenesis.
plgf structure
The molecules developed by ANBITION are multimeric, branched peptides containing non-natural amino acids. These peculiarities allow the rapid and easy chemical synthesis in spite of the dimensions (contain 15+ residues), increased avidity, a high structural flexibility and stability in biological media and in vivo.
generic tetrameric peptide